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Small Animal Imaging Core The presence of the Concorde Microsystems R4 small animal PET scanner enables scientist to perform non-invasive in vivo imaging in a variety of disease models in mice and rats. Small animal models, particularly genetically engineered mice, are increasingly recognized as powerful discovery tools in cancer, cardiac pharmaceutical and neurological research. PET imaging techniques are an important tool for providing data about biochemical, genetic or pharmaceutical processes in vivo and can be performed repetitively in the same animal. Many animal research models suffer from the critical limitation that animals must be sacrificed in order to perform tissue or molecular analysis before the full or long-term implications of the research become evident. This prevents researchers from observing in vivo the natural or induced evolution of the processes under study. The center has cyclotron and radiochemistry laboratory capable of producing the radiotracers used in PET imaging. The scientific staff at the center are able to produce radioisotopes necessary; perform the radiopharmaceutical chemistry required to generate animal PET data; and assist in experiment design and interpretation of images. Services: Bioluminescence/Fluorescence Imaging Location: |
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