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Immunotherapy for Cancer Treatment

Immunotherapy is the concept of using the body’s own immune system to treat disease.

Scientists within the LGRTC are focused on developing various immunotherapy approaches for the treatment of cancer.  These approaches are aimed at stimulating a patient’s immune system to reject and destroy tumors through the recognition of tumor-specific antigens. 

One way to stimulate the immune systems is using dendritic cells, a class of antigen presenting cells, to activate a cytotoxic response towards a tumor-specific antigen. Tumor antigens are presented by the dendritic cells, which in turn cause the immune system to target these antigens.

Another way to stimulate the immune system is through T-cell based immunotherapy.  This therapy uses T-cell based cytotoxic responses to attack cancer. T-cells are a type of lymphocyte that attack pathogens directly.

Related research:

Yan Cui, PhD
Alistair Ramsay, PhD
Jill Williams, PhD
Qian-Jin Zhang, PhD

© 2007 - Louisiana Gene Therapy Research Consortium | Last update: August 20, 2008