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Genetic Vaccines for Infectious Disease

Infectious diseases such tuberculosis and HIV/AIDS claim millions of lives a year worldwide. Developing vaccines to combat these diseases present scientific challenges.

Researchers at LCTRC are exploring new vaccination strategies against these diseases for which conventional vaccines have failed. One approach is based on the use of DNA vaccines to introduce a single artificially copied pathogen gene in order to produce an immunological response. The immune system will recognize the antigen as foreign and remember it, as in a traditional vaccination. Other methods include viral vectors that carry genes encoding vaccine antigens and the use of specific proteins or molecules as immunological targets.

Pamela Kozlowski, PhD
Alistair Ramsay, PhD

© 2007 - Louisiana Gene Therapy Research Consortium | Last update: August 20, 2008