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Virotherapy
Virotherapy is the concept of converting viruses into cancer-fighting agents by reprogramming viruses to only attack cancerous cells while sparing healthy cells. Scientists at LCTRC are manipulating viruses to selectively target and kill tumor cells. One approach is to construct viruses with specially generated adapter molecules that selectively attach, infect and kill cancer cells while leaving healthy cells alone. Viruses are also being genetically altered to selectively replicate inside tumor cells to cause tumor cell death. The high infection efficiencies, replication characteristics,
and transient lifespan of viruses make them greatly desirable
for use in many virotherapy strategies. |
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